Ethanol → HCID 58777580, compound

HRID 1542350Notes

Reaction equation

HRID 1542350 reaction equation
[CH3:36][S:37](=[O:38])(=[O:39])[N:40]1[CH2:41][CH2:42][CH:43]([NH2:46])[CH2:44][CH2:45]1.[CH3:56][CH2:57][OH:58].[CH:47]([N:48]([CH:49]([CH3:50])[CH3:51])[CH2:52][CH3:53])([CH3:54])[CH3:55].[F:29][C:30]([F:31])([F:32])[C:33]([OH:34])=[O:35].[NH2:1][c:2]1[n:3][c:4]([Cl:28])[n:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[c:11]([O:26][CH3:27])[c:12]([O:18][Si:19]([CH3:20])([CH3:21])[C:22]([CH3:23])([CH3:24])[CH3:25])[cH:13][c:14]([F:17])[c:15]1[F:16]>>[NH2:1][c:2]1[n:3][c:4]([NH:46][CH:43]2[CH2:42][CH2:41][N:40]([S:37]([CH3:36])(=[O:38])=[O:39])[CH2:45][CH2:44]2)[n:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[c:11]([O:26][CH3:27])[c:12]([O:18][Si:19]([CH3:20])([CH3:21])[C:22]([CH3:23])([CH3:24])[CH3:25])[cH:13][c:14]([F:17])[c:15]1[F:16]

Participants

6

Reactant 5

HCID 702EthanolHCID 6422Trifluoroacetic acidHCID 81531DiisopropylethylamineHCID 113558261-(Methanesulfonyl)piperidin-4-amineHCID 21070551(4-Amino-2-chloro-pyrimidin-5-yl)-[3-(tert-butyl-dimethyl-silanyloxy)-5,6-difluoro-2-methoxy-phenyl]-methanone

Product 1

HCID 58777580HCID 58777580, compound

Sources & evidence

ORD record
ord-1456abc25681481a8ffd1e389b0c082b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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