Dichloromethane → 2-(T-Butyldimethylsilyloxy)-4-bromoanisole

HRID 1542557Notes

Reaction equation

HRID 1542557 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([O:9][CH3:10])[c:6]([OH:8])[cH:7]1.[C:18]([CH3:19])([CH3:20])([CH3:21])[Si:22]([CH3:23])([CH3:24])[Cl:25].[CH2:26]([Cl:27])[Cl:28].[CH3:11][CH2:12][N:13]([CH2:14][CH3:15])[CH2:16][CH3:17].[CH3:29][N:30]([CH3:31])[c:32]1[cH:33][cH:34][n:35][cH:36][cH:37]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([O:9][CH3:10])[c:6]([O:8][Si:22]([C:18]([CH3:19])([CH3:20])[CH3:21])([CH3:23])[CH3:24])[cH:7]1

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 142844-(Dimethylamino)pyridineHCID 28928tert-Butyldimethylsilyl chlorideHCID 1422285-Bromo-2-methoxyphenol

Product 1

HCID 109800492-(T-Butyldimethylsilyloxy)-4-bromoanisole

Sources & evidence

ORD record
ord-a05984325e3c4d5ea979a53e51908f9a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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