4-Methylmorpholine → 3-Hydroxy-4-[(2,3,5,6-tetrachloro-pyridin-4-ylamino)-methyl]-piperidine-1-carboxylic acid benzyl ester
Reaction equation
[CH2:14]([c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1)[O:21][C:22](=[O:23])[N:24]1[CH2:25][CH:26]([OH:32])[CH:27]([CH2:30][NH2:31])[CH2:28][CH2:29]1.[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:33][N:34]1[CH2:35][CH2:36][O:37][CH2:38][CH2:39]1.[Cl:1][c:2]1[n:3][c:4]([Cl:13])[c:5]([Cl:12])[c:6]([N+:9]([O-:10])=[O:11])[c:7]1[Cl:8]>>[Cl:1][c:2]1[n:3][c:4]([Cl:13])[c:5]([Cl:12])[c:6]([NH:9][CH2:30][CH:27]2[CH:26]([OH:32])[CH2:25][N:24]([C:22]([O:21][CH2:14][c:15]3[cH:16][cH:17][cH:18][cH:19][cH:20]3)=[O:23])[CH2:29][CH2:28]2)[c:7]1[Cl:8]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-ca4edc46d6f04c828d4fcef39b81dcf5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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