Dichloromethane → (4-Aminonaphthalen-1-yloxy)-acetonitrile

HRID 154366Notes

Reaction equation

HRID 154366 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[cH:9][cH:10][c:11]([O:18][CH2:19][C:20]#[N:21])[c:12]2[cH:13][cH:14][cH:15][cH:16][c:17]12)([CH3:5])([CH3:6])[CH3:22].[CH3:30][CH2:31][O:32][C:33](=[O:34])[CH3:35].[Cl:36][CH2:37][Cl:38].[OH:23][C:24]([C:25]([F:26])([F:27])[F:28])=[O:29]>>[NH2:7][c:8]1[cH:9][cH:10][c:11]([O:18][CH2:19][C:20]#[N:21])[c:12]2[cH:13][cH:14][cH:15][cH:16][c:17]12

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 8857Ethyl AcetateHCID 59553417(4-Cyanomethoxynaphthalen-1-yl)-carbamic acid tert-butyl ester

Product 1

HCID 59553077(4-Aminonaphthalen-1-yloxy)-acetonitrile

Sources & evidence

ORD record
ord-46ae9f13e8d345f0b44dd01234740104
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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