Chloride → [2,4-Bis-(2,4-difluoro-phenoxy)-pyrimidin-5-yl]-(2-chloro-5-methylsulfanyl-phenyl)-methanone

HRID 1543843Notes

Reaction equation

HRID 1543843 reaction equation
[Br:1][c:2]1[c:3]([O:17][c:18]2[c:19]([F:25])[cH:20][c:21]([F:24])[cH:22][cH:23]2)[n:4][c:5]([O:8][c:9]2[c:10]([F:16])[cH:11][c:12]([F:15])[cH:13][cH:14]2)[n:6][cH:7]1.[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[CH:27]([Mg+:28])([CH3:29])[CH3:30].[Cl-:26].[Cl:31][c:32]1[c:33]([C:34](=[O:35])[Cl:36])[cH:37][c:38]([S:41][CH3:42])[cH:39][cH:40]1>>[c:2]1([C:34]([c:33]2[c:32]([Cl:31])[cH:40][cH:39][c:38]([S:41][CH3:42])[cH:37]2)=[O:35])[c:3]([O:17][c:18]2[c:19]([F:25])[cH:20][c:21]([F:24])[cH:22][cH:23]2)[n:4][c:5]([O:8][c:9]2[c:10]([F:16])[cH:11][c:12]([F:15])[cH:13][cH:14]2)[n:6][cH:7]1

Participants

6

Reactant 5

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 12793231HCID 12793231, compoundHCID 59834408HCID 59834408, compoundHCID 178461726HCID 178461726, compound

Product 1

HCID 57758593[2,4-Bis-(2,4-difluoro-phenoxy)-pyrimidin-5-yl]-(2-chloro-5-methylsulfanyl-phenyl)-methanone

Sources & evidence

ORD record
ord-3d1051261dcc4d6f99aa257c8c0b2559
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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