1,2-Dichloroethane → Ethyl 1-isopropylpiperidine-4-carboxylate

HRID 1544286Notes

Reaction equation

HRID 1544286 reaction equation
[C:16]([O:17][BH-:18]([O:19][C:20](=[O:21])[CH3:22])[O:23][C:24](=[O:25])[CH3:26])(=[O:27])[CH3:28].[CH3:12][C:13]([CH3:14])=[O:15].[Cl:35][CH2:36][CH2:37][Cl:38].[NH:1]1[CH2:2][CH2:3][CH:4]([C:5](=[O:6])[O:7][CH2:8][CH3:9])[CH2:10][CH2:11]1.[Na+:29].[Na+:34].[O-:30][C:31]([OH:32])=[O:33]>>[N:1]1([CH:13]([CH3:12])[CH3:14])[CH2:2][CH2:3][CH:4]([C:5](=[O:6])[O:7][CH2:8][CH3:9])[CH2:10][CH2:11]1

Participants

7

Reactant 6

HCID 111,2-DichloroethaneHCID 180AcetoneHCID 769Bicarbonate IonHCID 923Sodium ion2×HCID 70770Ethyl 4-piperidinecarboxylateHCID 2724942Triacetoxyborohydride

Product 1

HCID 19900430Ethyl 1-isopropylpiperidine-4-carboxylate

Sources & evidence

ORD record
ord-3a6dd3e911a44de59fbf054f60cdf6ec
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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