Dichloromethane → 4,6-Dichloro-2-(trifluoromethyl)quinazoline

HRID 1544491Notes

Reaction equation

HRID 1544491 reaction equation
[CH2:29]([Cl:30])[Cl:31].[CH3:22][CH2:23][N:24]([CH2:25][CH3:26])[CH2:27][CH3:28].[Cl:1][c:2]1[cH:3][c:4]2[c:5]([OH:16])[n:6][c:7]([C:12]([F:13])([F:14])[F:15])[n:8][c:9]2[cH:10][cH:11]1.[P:17]([Cl:18])([Cl:19])([Cl:20])=[O:21]>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([Cl:19])[n:6][c:7]([C:12]([F:13])([F:14])[F:15])[n:8][c:9]2[cH:10][cH:11]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 24813Phosphorus oxychlorideHCID 178517786HCID 178517786, compound

Product 1

HCID 210882754,6-Dichloro-2-(trifluoromethyl)quinazoline

Sources & evidence

ORD record
ord-5da8e019228e415aab447636b9556406
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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