Ammonium → Ethyl 1-[4-hydroxy-5-oxo-1-(1-phenylethyl)pyrrolidin-3-yl]cyclopropane-1-carboxylate

HRID 1544965Notes

Reaction equation

HRID 1544965 reaction equation
[CH2:13]([CH3:14])[O:15][C:16](=[O:17])[C:18]1([CH:21]2[CH2:22][C:23](=[O:34])[N:24]([CH:26]([CH3:27])[c:28]3[cH:29][cH:30][cH:31][cH:32][cH:33]3)[CH2:25]2)[CH2:19][CH2:20]1.[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH3:43][CH2:44][CH2:45][CH2:46][CH2:47][CH3:48].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[Cl-:36].[NH4+:37].[O:35].[O:38]1[CH2:39][CH2:40][CH2:41][CH2:42]1>>[CH2:13]([CH3:14])[O:15][C:16](=[O:17])[C:18]1([CH:21]2[CH:22]([OH:38])[C:23](=[O:34])[N:24]([CH:26]([CH3:27])[c:28]3[cH:29][cH:30][cH:31][cH:32][cH:33]3)[CH2:25]2)[CH2:19][CH2:20]1

Participants

9

Reactant 8

HCID 223AmmoniumHCID 312ChlorideHCID 962WaterHCID 7912DiisopropylamineHCID 8028TetrahydrofuranHCID 8058HexaneHCID 21260990HCID 21260990, compoundHCID 178418339Butyllithium

Product 1

HCID 21261042Ethyl 1-[4-hydroxy-5-oxo-1-(1-phenylethyl)pyrrolidin-3-yl]cyclopropane-1-carboxylate

Sources & evidence

ORD record
ord-5109fe6b7f9f41cd9a0f96fa3aafccbb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…