Trifluoroacetic acid → 3-(4-Imidazol-1-ylmethylphenyl)-5-butylthiophene-2-sulfonamide

HRID 1544967Notes

Reaction equation

HRID 1544967 reaction equation
[Br:45][c:46]1[cH:47][cH:48][c:49]([CH2:50][n:51]2[cH:52][cH:53][n:54][cH:55]2)[cH:56][cH:57]1.[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7].[c:37]1([O:38][CH3:39])[cH:40][cH:41][cH:42][cH:43][cH:44]1.[n:8]1([CH2:13][c:14]2[cH:15][cH:16][c:17](-[c:20]3[c:21]([S:29](=[O:30])(=[O:31])[NH:32][C:33]([CH3:34])([CH3:35])[CH3:36])[s:22][c:23]([CH2:25][CH2:26][CH2:27][CH3:28])[cH:24]3)[cH:18][cH:19]2)[cH:9][n:10][cH:11][cH:12]1>>[n:8]1([CH2:13][c:14]2[cH:15][cH:16][c:17](-[c:20]3[c:21]([S:29](=[O:30])(=[O:31])[NH2:32])[s:22][c:23]([CH2:25][CH2:26][CH2:27][CH3:28])[cH:24]3)[cH:18][cH:19]2)[cH:9][n:10][cH:11][cH:12]1

Participants

5

Reactant 4

HCID 6422Trifluoroacetic acidHCID 7519AnisoleHCID 29895571-(4-Bromobenzyl)-1H-imidazoleHCID 119940313-(4-Imidazol-1-ylmethylphenyl)-5-butyl-N-tert-butylthiophene-2-sulfonamide

Product 1

HCID 667751023-(4-Imidazol-1-ylmethylphenyl)-5-butylthiophene-2-sulfonamide

Sources & evidence

ORD record
ord-dc8901de9a1449aab86bb34d4da8b21e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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