Ammonia → 5-(Cyclooctyl-methyl)-spiro[indoline-3,4'-piperidin]-2-one
Reaction equation
[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[CH2:3]([c:4]1[cH:5][cH:6][cH:7][cH:8][cH:9]1)[N:10]1[C:11](=[O:33])[C:12]2([c:13]3[cH:14][c:15]([CH2:19][CH:20]4[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27]4)[cH:16][cH:17][c:18]31)[CH2:28][CH2:29][NH:30][CH2:31][CH2:32]2.[Cl-:34].[Li:2].[NH3:1].[NH4+:35]>>[NH:10]1[C:11](=[O:33])[C:12]2([c:13]3[cH:14][c:15]([CH2:19][CH:20]4[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27]4)[cH:16][cH:17][c:18]31)[CH2:28][CH2:29][NH:30][CH2:31][CH2:32]2Participants
7
Sources & evidence
- ORD record
- ord-36f2fcbc0a5d4cbba7da9702353a4688
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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