Dichloromethane → 2-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2,3-dihydro-1H-isoindol-1-one
Reaction equation
[C:31]1(=[O:32])[O:33][CH2:34][c:35]2[cH:36][cH:37][cH:38][cH:39][c:40]21.[CH3:1][Al:2]([CH3:3])[CH3:4].[CH3:50][S:51](=[O:52])(=[O:53])[Cl:54].[CH3:5][c:6]1[n:7][c:8]2[cH:9][cH:10][cH:11][c:12]([N:16]3[CH2:17][CH2:18][N:19]([CH2:22][CH2:23][c:24]4[cH:25][c:26]([NH2:27])[cH:28][cH:29][cH:30]4)[CH2:20][CH2:21]3)[c:13]2[cH:14][cH:15]1.[CH:41]([N:42]([CH2:43][CH3:44])[CH:45]([CH3:46])[CH3:47])([CH3:48])[CH3:49].[Cl:55][CH2:56][Cl:57]>>[CH3:5][c:6]1[n:7][c:8]2[cH:9][cH:10][cH:11][c:12]([N:16]3[CH2:17][CH2:18][N:19]([CH2:22][CH2:23][c:24]4[cH:25][c:26]([N:27]5[C:31](=[O:32])[c:40]6[c:35]([cH:36][cH:37][cH:38][cH:39]6)[CH2:34]5)[cH:28][cH:29][cH:30]4)[CH2:20][CH2:21]3)[c:13]2[cH:14][cH:15]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-a0294bb7aff24554bb83627d23f47c66
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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