Acetic Acid → 5-(2-Fluoro-4-iodophenylamino)-6,8-dimethylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione
Reaction equation
[CH3:32][C:33](=[O:34])[OH:35].[ClH:24].[I-:30].[I:31].[K+:29].[N:25]([O-:26])=[O:27].[NH2:1][c:2]1[cH:3][c:4]([F:23])[c:5]([NH:8][c:9]2[c:10]([CH3:22])[c:11](=[O:21])[n:12]([CH3:20])[c:13]3[n:14][cH:15][nH:16][c:17](=[O:19])[c:18]23)[cH:6][cH:7]1.[Na+:28].[OH2:36]>>[c:2]1([I:30])[cH:3][c:4]([F:23])[c:5]([NH:8][c:9]2[c:10]([CH3:22])[c:11](=[O:21])[n:12]([CH3:20])[c:13]3[n:14][cH:15][nH:16][c:17](=[O:19])[c:18]23)[cH:6][cH:7]1Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-8b5b0e8f56864aaab8e1f9567cdf521d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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