Dichloromethane → 3-Methyl 1-(4-nitrophenyl) 5-[4-(2,2,2-trifluoroethyl)phenyl]piperidine-1,3-dicarboxylate
Reaction equation
[CH3:22][CH2:23][N:24]([CH2:25][CH3:26])[CH2:27][CH3:28].[Cl:29][C:30](=[O:31])[O:32][c:33]1[cH:34][cH:35][c:36]([N+:39](=[O:40])[O-:41])[cH:37][cH:38]1.[Cl:42][CH2:43][Cl:44].[F:1][C:2]([CH2:3][c:4]1[cH:5][cH:6][c:7]([CH:10]2[CH2:11][CH:12]([C:16](=[O:17])[O:18][CH3:19])[CH2:13][NH:14][CH2:15]2)[cH:8][cH:9]1)([F:20])[F:21]>>[F:1][C:2]([CH2:3][c:4]1[cH:5][cH:6][c:7]([CH:10]2[CH2:11][CH:12]([C:16](=[O:17])[O:18][CH3:19])[CH2:13][N:14]([C:30](=[O:31])[O:32][c:33]3[cH:34][cH:35][c:36]([N+:39](=[O:40])[O-:41])[cH:37][cH:38]3)[CH2:15]2)[cH:8][cH:9]1)([F:20])[F:21]Participants
5
Sources & evidence
- ORD record
- ord-d637eb808ca94507a1e439651fbbf43c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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