Hydrochloric Acid → 4-fluoro-N-((1RS,2SR)-2-hydroxy-2-(1-naphthalenyl)-1-((4-(trifluoromethyl)phenyl)methyl)ethyl)benzamide
Reaction equation
[C:37](=[O:38])([O-:39])[OH:40].[CH3:42][CH2:43][O:44][C:45](=[O:46])[CH3:47].[ClH:1].[F:27][c:28]1[cH:29][cH:30][c:31]([C:32](=[O:33])[Cl:34])[cH:35][cH:36]1.[Na+:41].[OH2:48].[OH:2][CH:3]([CH:4]([CH2:5][c:6]1[cH:7][cH:8][c:9]([C:12]([F:13])([F:14])[F:15])[cH:10][cH:11]1)[NH2:16])[c:17]1[cH:18][cH:19][cH:20][c:21]2[cH:22][cH:23][cH:24][cH:25][c:26]12>>[OH:2][CH:3]([CH:4]([CH2:5][c:6]1[cH:7][cH:8][c:9]([C:12]([F:13])([F:14])[F:15])[cH:10][cH:11]1)[NH:16][C:32]([c:31]1[cH:30][cH:29][c:28]([F:27])[cH:36][cH:35]1)=[O:33])[c:17]1[cH:18][cH:19][cH:20][c:21]2[cH:22][cH:23][cH:24][cH:25][c:26]12Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-0e8bfea7dc504e84bb5342e909e595d4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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