Dichloromethane → (1-{[4-(4-Bromophenyl)-1,3-thiazol-2-yl]amino}cyclopropyl)methanol
Reaction equation
[Al+3:23].[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]([NH:13][C:14]3([C:17](=[O:18])[O:19][CH2:20][CH3:21])[CH2:15][CH2:16]3)[s:11][cH:12]2)[cH:6][cH:7]1.[CH2:33]([Cl:34])[Cl:35].[H-:22].[H-:25].[H-:26].[H-:27].[Li+:24].[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1>>[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]([NH:13][C:14]3([CH2:17][OH:18])[CH2:15][CH2:16]3)[s:11][cH:12]2)[cH:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-2c212330d4fd455f8ed8b8dc4e4162b5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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