Sodium ion → tert.-Butyl 3-{[6-(4-cyanophenyl)-5-(cyclopropylcarbonyl)-4-methyl-2-oxo-3-[3-(trifluoro-methyl)phenyl]-3,6-dihydropyrimidin-1(2H)-yl]methyl}benzoate
Reaction equation
[Br:34][CH2:35][c:36]1[cH:37][c:38]([C:39](=[O:40])[O:41][C:42]([CH3:43])([CH3:44])[CH3:45])[cH:46][cH:47][cH:48]1.[CH3:49][CH2:50][CH2:51][CH2:52][CH3:53].[CH:3]1([C:6](=[O:7])[C:8]2=[C:13]([CH3:14])[N:12]([c:15]3[cH:16][c:17]([C:21]([F:22])([F:23])[F:24])[cH:18][cH:19][cH:20]3)[C:11](=[O:25])[NH:10][CH:9]2[c:26]2[cH:27][cH:28][c:29]([C:30]#[N:31])[cH:32][cH:33]2)[CH2:4][CH2:5]1.[H-:1].[Na+:2].[O:54]1[CH2:55][CH2:56][CH2:57][CH2:58]1>>[CH:3]1([C:6](=[O:7])[C:8]2=[C:13]([CH3:14])[N:12]([c:15]3[cH:16][c:17]([C:21]([F:22])([F:23])[F:24])[cH:18][cH:19][cH:20]3)[C:11](=[O:25])[N:10]([CH2:35][c:36]3[cH:37][c:38]([C:39](=[O:40])[O:41][C:42]([CH3:43])([CH3:44])[CH3:45])[cH:46][cH:47][cH:48]3)[CH:9]2[c:26]2[cH:27][cH:28][c:29]([C:30]#[N:31])[cH:32][cH:33]2)[CH2:4][CH2:5]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-a5a00f85ff0f4a899f234d1ee08f636f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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