Acetate → 6-(2-(4-Methoxybenzyloxy)-4-methylpyridin-3-yl)quinazolin-2-amine

HRID 154653Notes

Reaction equation

HRID 154653 reaction equation
[C:58]([O-:59])(=[O:60])[CH3:61].[C:63]([O-:64])(=[O:65])[CH3:66].[CH3:29][O:30][c:31]1[cH:32][cH:33][c:34]([CH2:35][O:36][c:37]2[n:38][cH:39][cH:40][c:41]([CH3:44])[c:42]2[Br:43])[cH:45][cH:46]1.[CH3:52][CH2:53][O:54][C:55]([CH3:56])=[O:57].[CH3:9][C:10]1([CH3:11])[C:12]([CH3:13])([CH3:14])[O:15][B:16]([c:17]2[cH:18][c:19]3[cH:20][n:21][c:22]([NH2:27])[n:23][c:24]3[cH:25][cH:26]2)[O:28]1.[CH:47]([OH:48])([CH3:49])[CH3:50].[K+:6].[K+:7].[K+:8].[OH2:51].[P:1]([O-:2])([O-:3])([O-:4])=[O:5].[Pd+2:62]>>[c:17]1(-[c:42]2[c:37]([O:36][CH2:35][c:34]3[cH:33][cH:32][c:31]([O:30][CH3:29])[cH:46][cH:45]3)[n:38][cH:39][cH:40][c:41]2[CH3:44])[cH:18][c:19]2[cH:20][n:21][c:22]([NH2:27])[n:23][c:24]2[cH:25][cH:26]1

Participants

10

Reactant 9

HCID 175Acetate2×HCID 813Potassium Cation3×HCID 962WaterHCID 1061PhosphateHCID 3776IsopropanolHCID 8857Ethyl AcetateHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 160861386-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinazolin-2-amineHCID 670001042-(4-Methoxybenzyloxy)-3-bromo-4-methylpyridine

Product 1

HCID 669999546-(2-(4-Methoxybenzyloxy)-4-methylpyridin-3-yl)quinazolin-2-amine

Sources & evidence

ORD record
ord-902372564b314a1d9b60a5a9e443f4d7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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