Hydrochloric Acid → N-(5-Chloropyridin-2-yl)-2-(4-oxopiperidin-1-ylcarbonyl)aminobenzamide

HRID 1546676Notes

Reaction equation

HRID 1546676 reaction equation
[CH3:31][CH2:32][O:33][C:34]([CH3:35])=[O:36].[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9]([c:10]2[c:11]([NH:16][C:17](=[O:18])[N:19]3[CH2:20][CH2:21][C:22]4([O:23][CH2:26][CH2:25][O:24]4)[CH2:27][CH2:28]3)[cH:12][cH:13][cH:14][cH:15]2)=[O:29])[n:6][cH:7]1.[ClH:30].[O:37]1[CH2:38][CH2:39][O:40][CH2:41][CH2:42]1.[OH2:43]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9]([c:10]2[c:11]([NH:16][C:17](=[O:18])[N:19]3[CH2:20][CH2:21][C:22](=[O:23])[CH2:27][CH2:28]3)[cH:12][cH:13][cH:14][cH:15]2)=[O:29])[n:6][cH:7]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 962WaterHCID 8857Ethyl AcetateHCID 312751,4-DioxaneHCID 21906181N-(5-chloropyridin-2-yl)-2-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylcarbonyl)aminobenzamide

Product 1

HCID 21906655N-(5-Chloropyridin-2-yl)-2-(4-oxopiperidin-1-ylcarbonyl)aminobenzamide

Sources & evidence

ORD record
ord-c8aa159c57b349f983922555419882c9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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