Hydrochloric Acid → 5-(2-aminophenyl)-1-(2-methylpropyl)-1H-imidazole-4-carbonitrile
Reaction equation
[C:25](=[O:26])([O-:27])[O-:28].[CH3:31][O:32][CH2:33][CH2:34][O:35][CH3:36].[ClH:14].[I:1][c:2]1[c:3]([C:11]#[N:12])[n:4][cH:5][n:6]1[CH2:7][CH:8]([CH3:9])[CH3:10].[K+:29].[K+:30].[NH2:15][c:16]1[c:17]([B:22]([OH:23])[OH:24])[cH:18][cH:19][cH:20][cH:21]1.[OH2:13].[Pd:37]([Cl:38])[Cl:39].[c:40]1([P:41]([c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)[c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)[cH:54][cH:55][cH:56][cH:57][cH:58]1.[c:59]1([P:60]([c:61]2[cH:62][cH:63][cH:64][cH:65][cH:66]2)[c:67]2[cH:68][cH:69][cH:70][cH:71][cH:72]2)[cH:73][cH:74][cH:75][cH:76][cH:77]1>>[c:2]1(-[c:17]2[c:16]([NH2:15])[cH:21][cH:20][cH:19][cH:18]2)[c:3]([C:11]#[N:12])[n:4][cH:5][n:6]1[CH2:7][CH:8]([CH3:9])[CH3:10]Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-e986120d571f43439c71140797443967
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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