Hydroxide → N-(5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-5-(trifluoromethyl)picolinamide

HRID 1546796노트

반응식

[Br:1][c:2]1[c:3]([F:12])[c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][c:10]2[NH2:11].[Cl:29][CH2:30][Cl:31].[F:13][C:14]([c:15]1[cH:16][cH:17][c:18]([C:21](=[O:22])[OH:23])[n:19][cH:20]1)([F:24])[F:25].[Li+:27].[OH-:26].[OH2:28]>>[Br:1][c:2]1[c:3]([F:12])[c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][c:10]2[NH:11][C:21]([c:18]1[cH:17][cH:16][c:15]([C:14]([F:13])([F:24])[F:25])[cH:20][n:19]1)=[O:22]