Tetrahydrofuran → N-methyl-N-[2-(5-methyl-5-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4,5-dihydro-1,3-thiazol-2-yl)-1H-indol-7-yl]thiophene-2-sulfonamide
Reaction equation
[CH3:1][N:2]([S:3](=[O:4])(=[O:5])[c:6]1[s:7][cH:8][cH:9][cH:10]1)[c:11]1[cH:12][cH:13][cH:14][c:15]2[cH:16][c:17]([C:20]3=[N:24][CH2:23][C:22]([CH2:25][N:26]4[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]4)([CH3:32])[S:21]3)[nH:18][c:19]12.[CH3:33][CH2:34][N:35]([CH2:36][CH3:37])[CH2:38][CH3:39].[CH3:40][S:41]([Cl:42])(=[O:43])=[O:44].[O:45]1[CH2:46][CH2:47][CH2:48][CH2:49]1>>[CH3:1][N:2]([S:3](=[O:4])(=[O:5])[c:6]1[s:7][cH:8][cH:9][cH:10]1)[c:11]1[cH:12][cH:13][cH:14][c:15]2[cH:16][c:17]([C:20]3=[N:24][CH2:23][C:22]([CH2:25][N:26]4[CH2:27][CH2:28][N:29]([S:41]([CH3:40])(=[O:43])=[O:44])[CH2:30][CH2:31]4)([CH3:32])[S:21]3)[nH:18][c:19]12Participants
5
Sources & evidence
- ORD record
- ord-c638687f746c4181947e85b365cf7c8c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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