Tetrahydrofuran → 2,3-Dihydro-1-[(4-methoxy-2,6-dimethylphenyl)sulfonyl]-1H-indole-6-methanol

HRID 1546987Notes

Reaction equation

HRID 1546987 reaction equation
[BH4-:1].[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[CH3:3][O:4][c:5]1[cH:6][c:7]([CH3:28])[c:8]([S:12](=[O:13])(=[O:14])[N:15]2[CH2:16][CH2:17][c:18]3[cH:19][cH:20][c:21]([C:24](=[O:25])[O:26][CH3:27])[cH:22][c:23]32)[c:9]([CH3:11])[cH:10]1.[Li+:2]>>[CH3:3][O:4][c:5]1[cH:6][c:7]([CH3:28])[c:8]([S:12](=[O:13])(=[O:14])[N:15]2[CH2:16][CH2:17][c:18]3[cH:19][cH:20][c:21]([CH2:24][OH:25])[cH:22][c:23]32)[c:9]([CH3:11])[cH:10]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 28123BorohydrideHCID 28486Lithium ionHCID 59483781HCID 59483781, compound

Product 1

HCID 594838092,3-Dihydro-1-[(4-methoxy-2,6-dimethylphenyl)sulfonyl]-1H-indole-6-methanol

Sources & evidence

ORD record
ord-2a0dcc4923da4338af6b28fdcd9ab85e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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