Water → N-[(3-Chloro-pyrazin-2-yl)-(2-phenyl-quinolin-7-yl)-methyl]-acetamide

HRID 1547252Notes

Reaction equation

HRID 1547252 reaction equation
[CH3:35][C:36]([Cl:37])=[O:38].[CH3:43][N:44]([c:45]1[cH:46][cH:47][n:48][cH:49][cH:50]1)[CH3:51].[CH:26]([N:27]([CH2:28][CH3:29])[CH:30]([CH3:31])[CH3:32])([CH3:33])[CH3:34].[Cl:1][c:2]1[c:3]([CH:8]([c:9]2[cH:10][cH:11][c:12]3[cH:13][cH:14][c:15](-[c:19]4[cH:20][cH:21][cH:22][cH:23][cH:24]4)[n:16][c:17]3[cH:18]2)[NH2:25])[n:4][cH:5][cH:6][n:7]1.[Cl:40][CH2:41][Cl:42].[OH2:39]>>[Cl:1][c:2]1[c:3]([CH:8]([c:9]2[cH:10][cH:11][c:12]3[cH:13][cH:14][c:15](-[c:19]4[cH:20][cH:21][cH:22][cH:23][cH:24]4)[n:16][c:17]3[cH:18]2)[NH:25][C:36]([CH3:35])=[O:38])[n:4][cH:5][cH:6][n:7]1

Participants

7

Reactant 6

HCID 962WaterHCID 6344DichloromethaneHCID 6367Acetyl chlorideHCID 142844-(Dimethylamino)pyridineHCID 81531DiisopropylethylamineHCID 51051365(3-Chloropyrazin-2-yl)(2-phenylquinolin-7-yl)methanamine

Product 1

HCID 53629019N-[(3-Chloro-pyrazin-2-yl)-(2-phenyl-quinolin-7-yl)-methyl]-acetamide

Sources & evidence

ORD record
ord-2ce229bdd1a94150b3880306aed3214b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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