Chloride → 4-Bromo-3-(hydroxymethyl)benzonitrile
Reaction equation
[Br:1][c:2]1[c:3]([CH2:4][OH:5])[cH:6][c:7]([O:10][Si:11]([C:12]([CH3:13])([CH3:14])[CH3:15])([CH3:16])[CH3:17])[cH:8][cH:9]1.[CH3:19][O:20][CH2:21][P+:22]([c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1)([c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1)[c:35]1[cH:36][cH:37][cH:38][cH:39][cH:40]1.[CH3:41][C:42]([CH3:43])([O-:44])[CH3:45].[CH3:47][N:48]([CH3:49])[CH:50]=[O:51].[Cl-:18].[K+:46]>>[Br:1][c:2]1[c:3]([CH2:4][OH:5])[cH:6][c:7]([C:47]#[N:48])[cH:8][cH:9]1Participants
7
Sources & evidence
- ORD record
- ord-f9fa877f2d454c589e4a35aaa285abda
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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