Tetrahydrofuran → (1-Isopropyl-4,4,7-trimethyl-1,2,3,4-tetrahydroquinolin-6-yl)amine
Reaction equation
[Al+3:20].[H-:19].[H-:22].[H-:23].[H-:24].[Li+:21].[NH2:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][c:11]1[CH3:12])[N:8]([CH:13]([CH3:14])[CH3:15])[C:7](=[O:16])[CH2:6][C:5]2([CH3:17])[CH3:18].[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1>>[NH2:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][c:11]1[CH3:12])[N:8]([CH:13]([CH3:14])[CH3:15])[CH2:7][CH2:6][C:5]2([CH3:17])[CH3:18]Participants
6
Sources & evidence
- ORD record
- ord-374b62df37e2405d882ba4f3de0b3cb5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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