Cyclohexanecarboxylic acid → 1-(Methoxymethyl)cyclohexanecarboxylic acid

HRID 1548979Notes

Reaction equation

HRID 1548979 reaction equation
[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:30][O:31][CH2:32][Cl:33].[CH3:34][CH2:35][CH2:36][CH2:37][CH2:38][CH3:39].[CH:10]([N-:11][CH:12]([CH3:13])[CH3:14])([CH3:15])[CH3:16].[CH:1]1([C:7](=[O:8])[OH:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[CH:23]([NH:24][CH:25]([CH3:26])[CH3:27])([CH3:28])[CH3:29].[Li+:17].[Li:18][CH2:19][CH2:20][CH2:21][CH3:22]>>[C:1]1([C:7](=[O:8])[OH:9])([CH2:32][O:31][CH3:30])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

9

Reactant 8

HCID 7413Cyclohexanecarboxylic acidHCID 7864Chloromethyl Methyl EtherHCID 7912DiisopropylamineHCID 8028TetrahydrofuranHCID 8058HexaneHCID 28486Lithium ionHCID 5062348DiisopropylamideHCID 178418339Butyllithium

Product 1

HCID 184057031-(Methoxymethyl)cyclohexanecarboxylic acid

Sources & evidence

ORD record
ord-b0d585b8a5f1422ba8e7094ce4ffc325
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…