Ethylbenzene → 4-(2-Chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethylene)-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:32]([CH3:33])([CH3:34])([CH3:35])[O:36][C:37](=[O:38])[N:39]1[CH2:40][CH2:41][C:42](=[O:45])[CH2:43][CH2:44]1.[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH2:51]1[O:52][CH2:53][CH2:54][CH2:55]1.[CH3:1][O:2][P:3](=[O:4])([O:5][CH3:6])[CH2:7][c:8]1[cH:9][c:10]2[n:11][c:12]([Cl:23])[n:13][c:14]([N:17]3[CH2:18][CH2:19][O:20][CH2:21][CH2:22]3)[c:15]2[s:16]1.[CH3:56][CH2:57][CH2:58][CH2:59][CH2:60][CH2:61][CH3:62].[CH3:63][CH2:64][c:65]1[cH:66][cH:67][cH:68][cH:69][cH:70]1.[CH:24]([N-:25][CH:26]([CH3:27])[CH3:28])([CH3:29])[CH3:30].[Li+:31]>>[CH:7]([c:8]1[cH:9][c:10]2[n:11][c:12]([Cl:23])[n:13][c:14]([N:17]3[CH2:18][CH2:19][O:20][CH2:21][CH2:22]3)[c:15]2[s:16]1)=[C:42]1[CH2:41][CH2:40][N:39]([C:37]([O:36][C:32]([CH3:33])([CH3:34])[CH3:35])=[O:38])[CH2:44][CH2:43]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-d57321df0c7446bbb0724933515bac11
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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