Bicarbonate Ion → N-[4-Chloro-3-(tetrahydro-pyran-2-yloxymethyl)-pyridin-2-ylmethyl]-isobutyramide
Reaction equation
[BH4-:18].[C:25]([CH:26]([CH3:27])[CH3:28])(=[O:29])[Cl:30].[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:31][OH:32].[Cl:1][c:2]1[c:3]([CH2:10][O:11][CH:12]2[O:13][CH2:14][CH2:15][CH2:16][CH2:17]2)[c:4]([C:8]#[N:9])[n:5][cH:6][cH:7]1.[Na+:19].[Na+:24].[O-:20][C:21]([OH:22])=[O:23]>>[Cl:1][c:2]1[c:3]([CH2:10][O:11][CH:12]2[O:13][CH2:14][CH2:15][CH2:16][CH2:17]2)[c:4]([CH2:8][NH:9][C:25]([CH:26]([CH3:27])[CH3:28])=[O:29])[n:5][cH:6][cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-98e33daa86714ad7a68f3f3452b95ef8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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