Tetrahydrofuran → 6-Chloro-4-[4-(4-fluorophenylaminocarbonyl)piperazin-1-yl]quinoline
Reaction equation
[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:28][N:29]([c:30]1[cH:31][cH:32][n:33][cH:34][cH:35]1)[CH3:36].[Cl:1][c:2]1[cH:3][c:4]2[c:5]([N:12]3[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]3)[cH:6][cH:7][n:8][c:9]2[cH:10][cH:11]1.[F:18][c:19]1[cH:20][cH:21][c:22]([N:25]=[C:26]=[O:27])[cH:23][cH:24]1>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([N:12]3[CH2:13][CH2:14][N:15]([C:26]([NH:25][c:22]4[cH:21][cH:20][c:19]([F:18])[cH:24][cH:23]4)=[O:27])[CH2:16][CH2:17]3)[cH:6][cH:7][n:8][c:9]2[cH:10][cH:11]1Participants
5
Sources & evidence
- ORD record
- ord-ded24b0737af4783a999421dac3b0487
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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