Hydrochloric Acid → N-[1-(4-chloroisoquinolin-5-yl)sulfonylpyrrolidin-3-yl]-3-piperazin-1-ylpropanamide

HRID 1550001Notes

Reaction equation

HRID 1550001 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][N:11]([CH2:14][CH2:15][C:16](=[O:17])[NH:18][CH:19]2[CH2:20][N:21]([S:24](=[O:25])(=[O:26])[c:27]3[c:28]4[c:29]([Cl:37])[cH:30][n:31][cH:32][c:33]4[cH:34][cH:35][cH:36]3)[CH2:22][CH2:23]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[C:39]([O:40][C:41]([N:42]1[CH2:43][CH2:44][N:45]([CH2:46][CH2:47][C:48]([OH:49])=[O:50])[CH2:51][CH2:52]1)=[O:53])([CH3:54])([CH3:55])[CH3:56].[CH3:57][O:58][CH2:59][C:60]([OH:61])=[O:62].[ClH:38]>>[NH:8]1[CH2:9][CH2:10][N:11]([CH2:14][CH2:15][C:16](=[O:17])[NH:18][CH:19]2[CH2:20][N:21]([S:24](=[O:25])(=[O:26])[c:27]3[c:28]4[c:29]([Cl:37])[cH:30][n:31][cH:32][c:33]4[cH:34][cH:35][cH:36]3)[CH2:22][CH2:23]2)[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 12251Methoxyacetic AcidHCID 27356443-(1-TERT-BUTOXYCARBONYLPIPERAZIN-4-YL)PROPIONIC ACIDHCID 67243644Tert-butyl 4-[3-[[1-(4-chloroisoquinolin-5-yl)sulfonylpyrrolidin-3-yl]amino]-3-oxopropyl]piperazine-1-carboxylate

Product 1

HCID 67242049N-[1-(4-chloroisoquinolin-5-yl)sulfonylpyrrolidin-3-yl]-3-piperazin-1-ylpropanamide

Sources & evidence

ORD record
ord-6ab07ae2a8b74303b95082f8520db391
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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