Tetrahydrofuran → 3-bromo-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
Reaction equation
[Br:1][CH2:2][C:3]([C:4](=[O:5])[OH:6])([CH3:7])[OH:8].[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH3:27][CH2:28][N:29]([CH2:30][CH3:31])[CH2:32][CH3:33].[N+:13](=[O:14])([O-:15])[c:16]1[c:17]([C:23]([F:24])([F:25])[F:26])[cH:18][c:19]([NH2:20])[cH:21][cH:22]1.[S:9]([Cl:10])([Cl:11])=[O:12]>>[Br:1][CH2:2][C:3]([C:4](=[O:5])[NH:20][c:19]1[cH:18][c:17]([C:23]([F:24])([F:25])[F:26])[c:16]([N+:13](=[O:14])[O-:15])[cH:22][cH:21]1)([CH3:7])[OH:8]Participants
6
Sources & evidence
- ORD record
- ord-eaabf8bb4e2a4a87a36879208a7af250
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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