Acetate → 2-[4-[(2-chloro-4,4-difluoro-spiro[5H-thieno[2,3-c]pyran-7,4'-piperidine]-1'-yl)methyl]-3-methyl-pyrazol-1-yl]pyridine-3-carbaldehyde oxime
Reaction equation
[C:36]([O-:37])(=[O:38])[CH3:39].[CH3:41][CH2:42][OH:43].[Cl:1][c:2]1[cH:3][c:4]2[c:5]([s:32]1)[C:6]1([O:7][CH2:8][C:9]2([F:10])[F:11])[CH2:12][CH2:13][N:14]([CH2:17][c:18]2[c:19]([CH3:31])[n:20][n:21](-[c:23]3[n:24][cH:25][cH:26][cH:27][c:28]3[CH:29]=[O:30])[cH:22]2)[CH2:15][CH2:16]1.[ClH:33].[NH2:34][OH:35].[Na+:40]>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([s:32]1)[C:6]1([O:7][CH2:8][C:9]2([F:10])[F:11])[CH2:12][CH2:13][N:14]([CH2:17][c:18]2[c:19]([CH3:31])[n:20][n:21](-[c:23]3[n:24][cH:25][cH:26][cH:27][c:28]3[CH:29]=[N:34][OH:35])[cH:22]2)[CH2:15][CH2:16]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-80560103ffbd44099db9f9ded2ff141a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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