Hydrochloric Acid → Tert-butyl 2-(3-cyano-4-fluorophenyl)propanoate
Reaction equation
[C:13](#[N:14])[c:15]1[cH:16][c:17]([CH2:22][C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[cH:18][cH:19][c:20]1[F:21].[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH3:30][I:31].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[ClH:32]>>[CH3:1][CH:22]([c:17]1[cH:16][c:15]([C:13]#[N:14])[c:20]([F:21])[cH:19][cH:18]1)[C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29]Participants
7
Sources & evidence
- ORD record
- ord-41407ac0661a4415870a2a6e01a164e5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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