N,N-Dimethylglycine → 6-[3-[[2-(Dimethylamino)acetyl]amino]piperidin-1-yl]-2-[4-(morpholine-4-carbonyl)anilino]pyridine-3-carboxamide

HRID 1552763Notes

Reaction equation

HRID 1552763 reaction equation
[CH3:32][N:33]([CH2:34][C:35](=[O:36])[OH:37])[CH3:38].[CH:39]([N:40]([CH2:41][CH3:42])[CH:43]([CH3:44])[CH3:45])([CH3:46])[CH3:47].[Cl:77][CH2:78][Cl:79].[NH2:1][CH:2]1[CH2:3][N:4]([c:8]2[n:9][c:10]([NH:17][c:18]3[cH:19][cH:20][c:21]([C:24](=[O:25])[N:26]4[CH2:27][CH2:28][O:29][CH2:30][CH2:31]4)[cH:22][cH:23]3)[c:11]([C:12](=[O:13])[NH2:14])[cH:15][cH:16]2)[CH2:5][CH2:6][CH2:7]1.[O:72]=[CH:73][N:74]([CH3:75])[CH3:76].[P-:48]([F:49])([F:50])([F:51])([F:52])([F:53])[F:54].[n:55]1([O:56][C:57]([N:58]([CH3:59])[CH3:60])=[N+:61]([CH3:62])[CH3:63])[c:64]2[n:65][cH:66][cH:67][cH:68][c:69]2[n:70][n:71]1>>[NH:1]([CH:2]1[CH2:3][N:4]([c:8]2[n:9][c:10]([NH:17][c:18]3[cH:19][cH:20][c:21]([C:24](=[O:25])[N:26]4[CH2:27][CH2:28][O:29][CH2:30][CH2:31]4)[cH:22][cH:23]3)[c:11]([C:12](=[O:13])[NH2:14])[cH:15][cH:16]2)[CH2:5][CH2:6][CH2:7]1)[C:35]([CH2:34][N:33]([CH3:32])[CH3:38])=[O:36]

Participants

8

Reactant 7

HCID 673N,N-DimethylglycineHCID 6228DimethylformamideHCID 6344DichloromethaneHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 668328176-(3-Aminopiperidin-1-yl)-2-[4-(morpholine-4-carbonyl)anilino]pyridine-3-carboxamide

Product 1

HCID 668333756-[3-[[2-(Dimethylamino)acetyl]amino]piperidin-1-yl]-2-[4-(morpholine-4-carbonyl)anilino]pyridine-3-carboxamide

Sources & evidence

ORD record
ord-6ab66f6e5e3f49bca424def1e4737371
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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