Ammonium → tert-Butyl 4-(4-chlorophenyl)-4-cyanopiperidine-1-carboxylate
Reaction equation
[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[Cl-:27].[Cl:13][CH2:14][CH2:15][N:16]([C:17]([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23])[CH2:24][CH2:25][Cl:26].[Cl:3][c:4]1[cH:5][cH:6][c:7]([CH2:8][C:9]#[N:10])[cH:11][cH:12]1.[H-:1].[NH4+:28].[Na+:2]>>[Cl:3][c:4]1[cH:5][cH:6][c:7]([C:8]2([C:9]#[N:10])[CH2:14][CH2:15][N:16]([C:17]([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23])[CH2:24][CH2:25]2)[cH:11][cH:12]1Participants
8
Sources & evidence
- ORD record
- ord-efc6e861aff04b6ca5d767e10c36eb52
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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