Dimethyl Sulfoxide → Ethyl 4-methyl-4-(4-oxo-1-piperidyl)piperidine-1-carboxylate

HRID 1553416Notes

Reaction equation

HRID 1553416 reaction equation
[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[CH3:7][S:8]([CH3:9])=[O:10].[Cl:1][C:2]([C:3]([Cl:4])=[O:5])=[O:6].[Cl:37][CH2:38][Cl:39].[OH:11][CH:12]1[CH2:13][CH2:14][N:15]([C:18]2([CH3:29])[CH2:19][CH2:20][N:21]([C:24](=[O:25])[O:26][CH2:27][CH3:28])[CH2:22][CH2:23]2)[CH2:16][CH2:17]1>>[O:11]=[C:12]1[CH2:13][CH2:14][N:15]([C:18]2([CH3:29])[CH2:19][CH2:20][N:21]([C:24](=[O:25])[O:26][CH2:27][CH3:28])[CH2:22][CH2:23]2)[CH2:16][CH2:17]1

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 6344DichloromethaneHCID 8471TriethylamineHCID 65578Oxalyl chlorideHCID 57619818Ethyl 4-(4-hydroxy-1-piperidyl)-4-methyl-piperidine-1-carboxylate

Product 1

HCID 57619824Ethyl 4-methyl-4-(4-oxo-1-piperidyl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-e8ab89b2862145dd93c037a58cd2cf65
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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