Acetonitrile → (9-(3-(2-Hydroxyethyl)benzyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)(2-isopropylthiazol-4-yl)methanone
Reaction equation
[Br:29][CH2:30][c:31]1[cH:32][c:33]([CH2:37][CH2:38][OH:39])[cH:34][cH:35][cH:36]1.[CH3:40][CH2:41][N:42]([CH2:43][CH3:44])[CH2:45][CH3:46].[CH3:47][C:48]#[N:49].[CH:8]([CH3:9])([CH3:10])[c:11]1[s:12][cH:13][c:14]([C:16](=[O:17])[N:18]2[CH2:19][CH2:20][O:21][C:22]3([CH2:23]2)[CH2:24][CH2:25][NH:26][CH2:27][CH2:28]3)[n:15]1.[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7]>>[CH:8]([CH3:9])([CH3:10])[c:11]1[s:12][cH:13][c:14]([C:16](=[O:17])[N:18]2[CH2:19][CH2:20][O:21][C:22]3([CH2:23]2)[CH2:24][CH2:25][N:26]([CH2:30][c:31]2[cH:32][c:33]([CH2:37][CH2:38][OH:39])[cH:34][cH:35][cH:36]2)[CH2:27][CH2:28]3)[n:15]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-b422f61d3579476a921100b5577683f6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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