Dimethylformamide → tert-Butyl 4-(5-methyl-2-nitroanilino)piperidine-1-carboxylate

HRID 1553712Notes

Reaction equation

HRID 1553712 reaction equation
[CH3:35][N:36]([CH3:37])[CH:38]=[O:39].[CH:12]([N:13]([CH:14]([CH3:15])[CH3:16])[CH2:17][CH3:18])([CH3:19])[CH3:20].[F:1][c:2]1[cH:3][c:4]([CH3:11])[cH:5][cH:6][c:7]1[N+:8](=[O:9])[O-:10].[NH2:21][CH:22]1[CH2:23][CH2:24][N:25]([C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[CH2:26][CH2:27]1>>[c:2]1([NH:21][CH:22]2[CH2:23][CH2:24][N:25]([C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[CH2:26][CH2:27]2)[cH:3][c:4]([CH3:11])[cH:5][cH:6][c:7]1[N+:8](=[O:9])[O-:10]

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 67966Benzene, 2-fluoro-4-methyl-1-nitro-HCID 81531DiisopropylethylamineHCID 12682914-Amino-1-Boc-piperidine

Product 1

HCID 51072028tert-Butyl 4-(5-methyl-2-nitroanilino)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-5403d6d32cd242129a054b31654ec085
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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