Tetrahydrofuran → [2-(4-Hydroxyphenyl)-6-hydroxybenzofuran-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanol

HRID 1554190Notes

Reaction equation

HRID 1554190 reaction equation
[Al+3:36].[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[H-:35].[H-:38].[H-:39].[H-:40].[Li+:37].[OH:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[o:9][c:10]3[c:11]([c:12]2[C:13](=[O:14])[c:15]2[cH:16][cH:17][c:18]([O:21][CH2:22][CH2:23][N:24]4[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29]4)[cH:19][cH:20]2)[cH:30][cH:31][c:32]([OH:34])[cH:33]3)[cH:6][cH:7]1>>[OH:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[o:9][c:10]3[c:11]([c:12]2[CH:13]([OH:14])[c:15]2[cH:16][cH:17][c:18]([O:21][CH2:22][CH2:23][N:24]4[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29]4)[cH:19][cH:20]2)[cH:30][cH:31][c:32]([OH:34])[cH:33]3)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 99557562-(4-Hydroxyphenyl)-3-[4-[2-(piperidin-1-yl)ethoxy]benzoyl]-6-hydroxybenzofuran

Product 1

HCID 12968229[2-(4-Hydroxyphenyl)-6-hydroxybenzofuran-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanol

Sources & evidence

ORD record
ord-0a003cafddc941eaa61e65d01270f449
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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