Bicarbonate Ion → 1-Benzyl 4-methyl piperidine-1,4-dicarboxylate

HRID 1554531Notes

Reaction equation

HRID 1554531 reaction equation
[CH3:22][N:23]1[CH2:24][CH2:25][O:26][CH2:27][CH2:28]1.[CH3:29][C:30]#[N:31].[Cl:1][C:2](=[O:3])[O:4][CH2:5][c:6]1[cH:7][cH:8][cH:9][cH:10][cH:11]1.[NH:12]1[CH2:13][CH2:14][CH:15]([C:18](=[O:19])[O:20][CH3:21])[CH2:16][CH2:17]1.[Na+:36].[O-:32][C:33]([OH:34])=[O:35]>>[C:2](=[O:3])([O:4][CH2:5][c:6]1[cH:7][cH:8][cH:9][cH:10][cH:11]1)[N:12]1[CH2:13][CH2:14][CH:15]([C:18](=[O:19])[O:20][CH3:21])[CH2:16][CH2:17]1

Participants

7

Reactant 6

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 6342AcetonitrileHCID 79724-MethylmorpholineHCID 10387Benzyl chloroformateHCID 424914Methyl isonipecotate

Product 1

HCID 15125441-Benzyl 4-methyl piperidine-1,4-dicarboxylate

Sources & evidence

ORD record
ord-a15c4862fefe40afb944af4b9b8d1f83
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…