Methylamine → Methyl 6-(3-chloro-4-fluorobenzyl)-4-hydroxy-2-[4-(methylamino)butyl]-3,5-dioxo-2,3,5,6,7,8-hexahydro-2,6-naphthyridine-1-carboxylate
Reaction equation
[CH2:40]([N+:41]([CH2:42][CH2:43][CH2:44][CH3:45])([CH2:46][CH2:47][CH2:48][CH3:49])[CH2:50][CH2:51][CH2:52][CH3:53])[CH2:54][CH2:55][CH3:56].[CH3:32][NH2:33].[Cl:1][CH2:2][CH2:3][CH2:4][CH2:5][n:6]1[c:7]([C:28](=[O:29])[O:30][CH3:31])[c:8]2[c:13]([c:14]([OH:17])[c:15]1=[O:16])[C:12](=[O:18])[N:11]([CH2:19][c:20]1[cH:21][c:22]([Cl:27])[c:23]([F:26])[cH:24][cH:25]1)[CH2:10][CH2:9]2.[I-:39].[O:34]1[CH2:35][CH2:36][CH2:37][CH2:38]1>>[CH2:2]([CH2:3][CH2:4][CH2:5][n:6]1[c:7]([C:28](=[O:29])[O:30][CH3:31])[c:8]2[c:13]([c:14]([OH:17])[c:15]1=[O:16])[C:12](=[O:18])[N:11]([CH2:19][c:20]1[cH:21][c:22]([Cl:27])[c:23]([F:26])[cH:24][cH:25]1)[CH2:10][CH2:9]2)[NH:33][CH3:32]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-8c60fea178044907932943d681f3f4e4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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