Chloroform → 1-O-tert-butyl 3-O-ethyl 4-methylsulfonyloxypiperidine-1,3-dicarboxylate

HRID 1554908Notes

Reaction equation

HRID 1554908 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([C:15](=[O:16])[O:17][CH2:18][CH3:19])[CH:11]([OH:14])[CH2:12][CH2:13]1.[CH3:20][CH2:21][N:22]([CH2:23][CH3:24])[CH2:25][CH3:26].[CH3:27][S:28]([Cl:29])(=[O:30])=[O:31].[CH3:36][N:37]([CH3:38])[c:39]1[cH:40][cH:41][n:42][cH:43][cH:44]1.[CH:32]([Cl:33])([Cl:34])[Cl:35]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([C:15](=[O:16])[O:17][CH2:18][CH3:19])[CH:11]([O:14][S:28]([CH3:27])(=[O:30])=[O:31])[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 6212ChloroformHCID 8471TriethylamineHCID 142844-(Dimethylamino)pyridineHCID 31297Methanesulfonyl chlorideHCID 54102192O1-tert-butyl O3-ethyl 4-hydroxypiperidine-1,3-dicarboxylate

Product 1

HCID 865899061-O-tert-butyl 3-O-ethyl 4-methylsulfonyloxypiperidine-1,3-dicarboxylate

Sources & evidence

ORD record
ord-4c55b4260916463db834288ec20cfca7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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