Diethyl Ether → 1-[(5-Bromo-2-chloro-phenyl)methyl]-2,3-difluoro-4-methoxy-benzene

HRID 1555286Notes

Reaction equation

HRID 1555286 reaction equation
[B:33]([F:34])([F:35])[F:36].[Br:1][c:2]1[cH:3][cH:4][c:5]([Cl:20])[c:6]([CH:8]([OH:9])[c:10]2[c:11]([F:19])[c:12]([F:18])[c:13]([O:16][CH3:17])[cH:14][cH:15]2)[cH:7]1.[CH2:21]([SiH:22]([CH2:23][CH3:24])[CH2:25][CH3:26])[CH3:27].[CH2:28]([O:29][CH2:30][CH3:31])[CH3:32].[CH2:37]([Cl:38])[Cl:39]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([Cl:20])[c:6]([CH2:8][c:10]2[c:11]([F:19])[c:12]([F:18])[c:13]([O:16][CH3:17])[cH:14][cH:15]2)[cH:7]1

Participants

6

Reactant 5

HCID 3283Diethyl EtherHCID 6344DichloromethaneHCID 6356Boron trifluorideHCID 12052TriethylsilaneHCID 86685108(5-Bromo-2-chloro-phenyl)-(2,3-difluoro-4-methoxy-phenyl)methanol

Product 1

HCID 866851071-[(5-Bromo-2-chloro-phenyl)methyl]-2,3-difluoro-4-methoxy-benzene

Sources & evidence

ORD record
ord-7b21b647e89a4d9da035e6ac8be0dc69
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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