Toluene → Ethyl 1-benzoylpiperidine-4-carboxylate

HRID 1555578Notes

Reaction equation

HRID 1555578 reaction equation
[C:19]([c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)(=[O:26])[Cl:27].[CH3:12][CH2:13][N:14]([CH2:15][CH3:16])[CH2:17][CH3:18].[CH3:28][c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1.[NH:1]1[CH2:2][CH2:3][CH:4]([C:7](=[O:8])[O:9][CH2:10][CH3:11])[CH2:5][CH2:6]1>>[N:1]1([C:19]([c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)=[O:26])[CH2:2][CH2:3][CH:4]([C:7](=[O:8])[O:9][CH2:10][CH3:11])[CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 1140TolueneHCID 7412Benzoyl chlorideHCID 8471TriethylamineHCID 70770Ethyl 4-piperidinecarboxylate

Product 1

HCID 735824Ethyl 1-benzoylpiperidine-4-carboxylate

Sources & evidence

ORD record
ord-3493c4e605e24936a62615d9b589475a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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