Bromide ion → 2,3-Difluoro-N-(2-fluoro-4-iodophenyl)-6-[(3-methylidene azetidin-1-yl)carbonyl]aniline
Reaction equation
[Br-:37].[CH3:1][C:2]([CH3:3])([O-:4])[CH3:5].[CH3:31][CH2:32][O:33][C:34](=[O:35])[CH3:36].[CH3:38][P+:39]([c:40]1[cH:41][cH:42][cH:43][cH:44][cH:45]1)([c:46]1[cH:47][cH:48][cH:49][cH:50][cH:51]1)[c:52]1[cH:53][cH:54][cH:55][cH:56][cH:57]1.[F:7][c:8]1[c:9]([NH:22][c:23]2[c:24]([F:30])[cH:25][c:26]([I:29])[cH:27][cH:28]2)[c:10]([C:15](=[O:16])[N:17]2[CH2:18][C:19](=[O:21])[CH2:20]2)[cH:11][cH:12][c:13]1[F:14].[K+:6].[O:58]1[CH2:59][CH2:60][CH2:61][CH2:62]1>>[CH2:1]=[C:19]1[CH2:18][N:17]([C:15]([c:10]2[c:9]([NH:22][c:23]3[c:24]([F:30])[cH:25][c:26]([I:29])[cH:27][cH:28]3)[c:8]([F:7])[c:13]([F:14])[cH:12][cH:11]2)=[O:16])[CH2:20]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-c009dcc18f5743fe93b9325313faa17b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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