4-Chloropyridine → 4-Chloro-3-[4-(4-chlorophenyl)-2-thiazolyl]pyridine

HRID 1556699Notes

Reaction equation

HRID 1556699 reaction equation
[CH3:9][CH:10]([N-:11][CH:12]([CH3:13])[CH3:14])[CH3:15].[Cl:16][c:17]1[cH:18][cH:19][c:20](-[c:23]2[n:24][c:25]([Br:28])[s:26][cH:27]2)[cH:21][cH:22]1.[Cl:1][c:2]1[cH:3][cH:4][n:5][cH:6][cH:7]1.[Li+:8]>>[Cl:1][c:2]1[c:3](-[c:25]2[n:24][c:23](-[c:20]3[cH:19][cH:18][c:17]([Cl:16])[cH:22][cH:21]3)[cH:27][s:26]2)[cH:4][n:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 122884-ChloropyridineHCID 28486Lithium ionHCID 5062348DiisopropylamideHCID 220497472-Bromo-4-(4-chlorophenyl)-1,3-thiazole

Product 1

HCID 220496904-Chloro-3-[4-(4-chlorophenyl)-2-thiazolyl]pyridine

Sources & evidence

ORD record
ord-5cef7dc88b644f37a191ffb647ba3240
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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