Trifluoroacetic acid → 4-(cis-4-Tert-butylcyclohexylamino)-6-ethyl-5-fluoropyrimidine
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[CH:5]1[CH2:6][CH2:7][CH:8]([NH:11][c:12]2[n:13][cH:14][n:15][c:16]([CH2:18][CH3:19])[cH:17]2)[CH2:9][CH2:10]1.[F:20].[OH:21][C:22]([C:23]([F:24])([F:25])[F:26])=[O:27]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[CH:5]1[CH2:6][CH2:7][CH:8]([NH:11][c:12]2[n:13][cH:14][n:15][c:16]([CH2:18][CH3:19])[c:17]2[F:25])[CH2:9][CH2:10]1Participants
4
Sources & evidence
- ORD record
- ord-f5b8d66f94e546ffbd8cf76ae9df8dd4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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