Water → Tert-butyl 3-[6-chloro-2-(2,2-dimethylpropanamido)pyridin-3-yl]-3-hydroxypropanoate
Reaction equation
[C:11]([CH3:12])(=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18].[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[CH3:1][SiH:2]([CH3:3])[N:4]([CH3:5])[Si:6]([CH3:7])([CH3:8])[CH3:9].[CH3:41][CH2:42][O:43][C:44](=[O:45])[CH3:46].[Cl:19][c:20]1[cH:21][cH:22][c:23]([CH:33]=[O:34])[c:24]([NH:26][C:27]([C:28]([CH3:29])([CH3:30])[CH3:31])=[O:32])[n:25]1.[Li:10].[OH2:35]>>[C:11]([CH2:12][CH:33]([c:23]1[cH:22][cH:21][c:20]([Cl:19])[n:25][c:24]1[NH:26][C:27]([C:28]([CH3:29])([CH3:30])[CH3:31])=[O:32])[OH:34])(=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-d3416ae952c54218a3acab2c3135b628
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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