Tetrahydrofuran → 3-(Aminomethyl)-2,6-dichloro-5-fluoroaniline
Reaction equation
[Al+3:15].[CH2:20]1[O:21][CH2:22][CH2:23][CH2:24]1.[Cl:1][c:2]1[c:3]([C:4](=[O:5])[NH2:6])[cH:7][c:8]([F:13])[c:9]([Cl:12])[c:10]1[NH2:11].[H-:14].[H-:17].[H-:18].[H-:19].[Li+:16]>>[Cl:1][c:2]1[c:3]([CH2:4][NH2:6])[cH:7][c:8]([F:13])[c:9]([Cl:12])[c:10]1[NH2:11]Participants
6
Sources & evidence
- ORD record
- ord-9fac05fc0a814a678607ae604ea5f32d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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