Dimethylformamide → Ethyl 1-(2-fluorobenzyl)-5-{[(2methyl-1,3-dioxolan-2-yl)acetyl]amino}-1H-indole-2-carboxylate

HRID 1557765Notes

Reaction equation

HRID 1557765 reaction equation
[CH3:1][C:2]1([CH2:7][C:8](=[O:9])[OH:10])[O:3][CH2:4][CH2:5][O:6]1.[CH:35]([N:36]([CH2:37][CH3:38])[CH:39]([CH3:40])[CH3:41])([CH3:42])[CH3:43].[NH2:44][c:45]1[cH:46][c:47]2[cH:48][c:49]([C:62](=[O:63])[O:64][CH2:65][CH3:66])[n:50]([CH2:54][c:55]3[c:56]([F:61])[cH:57][cH:58][cH:59][cH:60]3)[c:51]2[cH:52][cH:53]1.[O:67]=[CH:68][N:69]([CH3:70])[CH3:71].[P-:11]([F:12])([F:13])([F:14])([F:15])([F:16])[F:17].[n:18]1([O:19][C:20]([N:21]([CH3:22])[CH3:23])=[N+:24]([CH3:25])[CH3:26])[c:27]2[n:28][cH:29][cH:30][cH:31][c:32]2[n:33][n:34]1>>[CH3:1][C:2]1([CH2:7][C:8](=[O:10])[NH:44][c:45]2[cH:46][c:47]3[cH:48][c:49]([C:62](=[O:63])[O:64][CH2:65][CH3:66])[n:50]([CH2:54][c:55]4[c:56]([F:61])[cH:57][cH:58][cH:59][cH:60]4)[c:51]3[cH:52][cH:53]2)[O:3][CH2:4][CH2:5][O:6]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 5600442-(2-Methyl-1,3-dioxolan-2-yl)acetic acidHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 22144678Ethyl 5-amino-1-(2-fluorobenzyl)-1H-indole-2-carboxylate

Product 1

HCID 22144636Ethyl 1-(2-fluorobenzyl)-5-{[(2methyl-1,3-dioxolan-2-yl)acetyl]amino}-1H-indole-2-carboxylate

Sources & evidence

ORD record
ord-668f80c4e0a54f15b811336424c86ff4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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